Definition: What is Wittig Reaction?
Witting reaction is a tool for organic synthesis of an alkene. It is a type of chemical reaction which is used to produce alkene from aldehyde or ketone. During this reaction, aylide is added to the aldehyde or ketone, and the double bond is formed precisely in the same position as itwas in the original carbonyl compound. Ylide is defined as a compound with opposite charges on adjacent atoms, both of which have complete octets. The ylide used in this case is triphenylphosphonium, also called Wittig reagent [1-4].
Example of Witting Reaction
Mechanism for Preparation of Ylide for Witting Reaction [5,6]
Mechanism of Wittig Reaction [5,6]
Uses, Applications, and Importance of Wittig Reaction
The witting reaction is the most general method for the synthesis of alkenes. The reaction is still a relevant area of study today due to its selective capabilities and ability to be performed in moderate conditions.
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